IJCEP Copyright © 2007-All rights reserved.
Int J Clin Exp Pathol 2010;3(7):730-735

Case Report
Primary lung seminoma in a 76-year-old man: a case report

Shaojun Zhu, Yanhong Li, Guiqiu Liu, Xiujuan Han, Li Gong, Li Yao, Miao Lan, Wei Zhang

Department of Pathology, Tangdu Hospital, the Fourth Military Medical University, Xi’an, Shanxi 710038, P.R. China

Received May 25, 2010; accepted July 16, 2010; available online August 15, 2010

Abstract: Background: Seminoma is a rare event in old male population. In this report, we present a rare case of primary seminoma in the lung
of a 76-years-old man. Case presentation: The patient was a 76-year-old man admitted with respiratory tract symptom and hemoptysis. The
Chest Routine Scan and CT showed there was a consolidation area in the basal segments at the lower lobe of left lung. Bronchoscope also
exhibited a neoplasm in left lung. During left lower lobectomy, we found that adherence occurred widely in left thoracic wall, and the pleural
membrane was shrinkage. No chemotherapy or radiotherapy was given. Patient was died at 140 days after the surgery mainly due to the
dyscrasia and secondary seminoma in left 7th to 9th ribs. Placental alkaline phosphatase (PLAP) and CD117 were found to be positive with
immunohistochemical studies. Along with other evidences, this case was identified as the manifestations of seminoma. Conclusion: Although
primary seminoma of the lung is rare in old male population, the diagnosis should be taken into serious consideration in order to improve the
treatment. And in this case, primary lung seminoma is associated with high degree of malignancy and metastasis. (IJCEP1005006).

Keywords: Primary seminoma, lung, immunohistochemistry

Full text PDF

Address all correspondence to:
Wei Zhang, MD
Department of Pathology, Tangdu Hospital
The Fourth Military Medical University
Xi’an, Shanxi 710038
P.R. China
Tel: +86-029 84777467
Fax: 029 83552079
E-mail: zhusjly@fmmu.edu.cn