IJCEP Copyright © 2007-All rights reserved.
Int J Clin Exp Pathol 2011;4(2):197-199

Case Report
The importance of fine needle aspiration in conjunction with radiologic examination in
the evaluation of granular cell tumor presenting as a thyroid mass: a case report

Jing Liu, Savitri Krishnamouthy

Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston Medical School, Houston, Texas,
USA; Division of Pathology and Laboratory Medicine, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

Received November 11, 2010; accepted January 15, 2011; Epub January 30, 2011; published February 15, 2011

Abstract: Granular cell tumor presenting as a thyroid mass is very rare. It may arise from the thyroid gland or from the tissues/organs adjacent
to the thyroid gland. It may cytologically mimick other common thyroid tumors. The accurate evaluation of these tumors may be important for
management. We describe a granular cell tumor arising from the tissue adjacent to the thyroid gland and with multiple organ/tissue
involvement in a 27-year-old woman with an initial presentation of a thyroid mass. The diagnosis was made preoperatively by fine needle
aspiration and immunocytochemial stains in conjunction with radiological examination. To our knowledge, there is no previous report of such
cases in the literature and the importance of fine needle aspiration in conjunction with radiologic examination in the evaluation of granular cell
tumor presenting as a thyroid mass has not been well addressed. (IJCEP1011002).

Keywords: Cytology, fine needle aspiration (FNA), granular cell tumor, immunostaining, thyroid gland, radiography

Full text PDF

Address all correspondence to:
Dr. Jing Liu
Department of Pathology & Laboratory
University of Texas Medical School at Houston
6431 Fannin Street, MSB 2.260A
Houston, TX 77030, USA.
Tel: (713) 500-5327, Fax: (713) 500-0733
E-mail:
jing.liu.1@uth.tmc.edu