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Int J Clin Exp Pathol 2011;4(8):794-796
Case Report
Papillary squamous cell carcinoma of the oral cavity with acantholytic and
pseudovascular features
Tadashi Terada
Department of Pathology, Shizuoka City Shimizu Hospital, Shizuoka, Japan.
Received August 12, 2011; accepted October 11, 2011; Epub November 3, 2011; Published November 30, 2011
Abstract: Herein reported is a case of papillary squamous cell carcinoma (PSCC) in the oral cavity with features of koilocytosis, acantholysis
and pseudovascular structure. A 73-year-old woman consulted to our hospital because of a tumor in the right mandibular gum. Physical
examination revealed an exophytic papillary tumor of the right mandibular gum, and a biopsy was performed. The biopsy revealed squamous
cell carcinoma. No metastases were found by various imaging techniques. Therefore, resection of the tumor and mandibular bone was
performed. Grossly, the tumor was exophytic and papillary, and measured 2 x 2 x 1 cm. The mandibular bone was free from tumor invasion.
Microscopically, the tumor showed exophytic papillary proliferation with fibrovascular cores and consisted of atypical squamous epithelial cells.
The tumor cells showed hyperchromasia, nuclear atypia, mitotic figures, apoptotic bodies, cancer pearls, and individual keratinization. Mild
stromal invasion was seen. Therefore, PSCC was diagnosed. Koilocytosis, acantholytic features, and pseudovascular features were
recognized in some areas. The lateral and vertical margins are negative for tumor cells. The mandibular bone was negative for tumor invasion.
The pathological diagnosis was PSCC with koilocytotic, acantholytic and pseudovascular features. The patient was healthy and free from tumor
three months after the operation. (IJCEP1108007).
Keywords: Papillary squamous cell carcinoma, oral cavity
Full text PDF
Address all correspondence to:
Tadashi Terada, MD, PhD,
Department of Pathology
Shizuoka City Shimizu Hospital
Miyakami 1231, Shimizu-Ku, Shizuoka, 424-8636, Japan.
Tel: 81-54-336-1111, Fax: 81-54-336-1315
E-mail: piyo0111jp@yahoo.co.jp
Case Report
Papillary squamous cell carcinoma of the oral cavity with acantholytic and
pseudovascular features
Tadashi Terada
Department of Pathology, Shizuoka City Shimizu Hospital, Shizuoka, Japan.
Received August 12, 2011; accepted October 11, 2011; Epub November 3, 2011; Published November 30, 2011
Abstract: Herein reported is a case of papillary squamous cell carcinoma (PSCC) in the oral cavity with features of koilocytosis, acantholysis
and pseudovascular structure. A 73-year-old woman consulted to our hospital because of a tumor in the right mandibular gum. Physical
examination revealed an exophytic papillary tumor of the right mandibular gum, and a biopsy was performed. The biopsy revealed squamous
cell carcinoma. No metastases were found by various imaging techniques. Therefore, resection of the tumor and mandibular bone was
performed. Grossly, the tumor was exophytic and papillary, and measured 2 x 2 x 1 cm. The mandibular bone was free from tumor invasion.
Microscopically, the tumor showed exophytic papillary proliferation with fibrovascular cores and consisted of atypical squamous epithelial cells.
The tumor cells showed hyperchromasia, nuclear atypia, mitotic figures, apoptotic bodies, cancer pearls, and individual keratinization. Mild
stromal invasion was seen. Therefore, PSCC was diagnosed. Koilocytosis, acantholytic features, and pseudovascular features were
recognized in some areas. The lateral and vertical margins are negative for tumor cells. The mandibular bone was negative for tumor invasion.
The pathological diagnosis was PSCC with koilocytotic, acantholytic and pseudovascular features. The patient was healthy and free from tumor
three months after the operation. (IJCEP1108007).
Keywords: Papillary squamous cell carcinoma, oral cavity
Full text PDF
Address all correspondence to:
Tadashi Terada, MD, PhD,
Department of Pathology
Shizuoka City Shimizu Hospital
Miyakami 1231, Shimizu-Ku, Shizuoka, 424-8636, Japan.
Tel: 81-54-336-1111, Fax: 81-54-336-1315
E-mail: piyo0111jp@yahoo.co.jp
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