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Int J Clin Exp Pathol 2012;5(3):260-263

Case Report
One patient with double lymphomas: simultaneous gastric MALT lymphoma and ileal
diffuse large B-cell lymphoma

Tadashi Terada

Departments of Pathology, Shizuoka City Shimizu Hospital, Shizuoka, Japan.

Received October 25, 2011; accepted February 27, 2012; Epub March 25, 2012; Published March 30, 2012

Abstract: Multiple different lymphomas in a single person are very rare. The author herein reports the case of a 69-year-old Japanese woman
with double gastrointestinal lymphoma. The patient presented with epigastralgia. Endoscopic examination revealed erosions and elevation of
the gastric body and a large ulcerated tumor of the terminal ileum. Biopsies were obtained from these lesions. The gastric lesion was MALT
lymphoma with monocytoid B-cell proliferation and lymphoepithelial lesions. Light chain restriction was present. Helicobacter pylori were
present on Giemsa stain. The gastric lesions did not regress despite of therapy, which were confirmed by follow-up biopsy. The ileal lesion
was obvious diffuse large B-cell lymphoma. The lesion regressed by chemotherapy. The patient is now alive 3 years after the first presentation.


Keywords: Double lymphoma, gastric MALT  lymphoma, ileal diffuse large B-cell lymphoma

Address all correspondence to:
Dr. Tadashi Terada
Department of Pathology, Shizuoka City Shimizu Hospital
Miyakami 1231 Shimizu-Ku, Shizuoka 424-8636, Japan.
Tel: 81-54-336-1111; Fax: 81-54-336-1315
E-mail: piyo0111jp@yahoo.co.jp