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Int J Clin Exp Pathol 2012;5(3):243-246

Case Report
Left-sided gastroschisis with placenta findings: case report and literature review

Yang Shi, Christine K Farinelli, Michael S Chang, Philip M Carpenter

The Departments of Pathology, Obstetrics and Gynecology and Pediatrics, The University of California, Irvine, CA, USA.

Received February 13, 2012; accepted March 3, 2012; Epub March 25, 2012; Published March 30, 2012

Abstract: Gastroschisis is a congenital abdominal-wall defect that typically occurs to the right of the umbilicus. Only twenty-one cases of
left-sided gastroschisis have been described in the literature. Here we report a large left-sided gastroschisis with pulmonary hypoplasia,
scoliosis, ventricular septal defect and absence of gallbladder. Section of placental membranes revealed vacuolization of the amnion, without
increased macrophage infiltration of the chorion. Postmortem comparative genomic hybridization micro array did not identify a specific genetic
abnormality. Some of the previously reported cases were complicated by additional abnormalities and comparisons with these cases are
discussed. (IJCEP1202006

Keywords: Left gastroschisis, pulmonary hypoplasia, scoliosis, ventricular septal defect

Address all correspondence to:
Dr. Yang Shi
Department of Pathology
University of California, Irvine Medical Center
Building 1, Room 3003,101 The City Dr.
Orange CA 92868, USA.
Tel: (714) 456-6141; Fax: (714) 456-5873
E-mail: Shiy2@uci.edu