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Int J Clin Exp Pathol 2012;5(3):270-273
99mTc-RBC Scintigraphy for diagnosis of intestinal stromal tumor hemorrhage: a case
Jiang Wang, Rong Zhao
1Department of General Surgery, Urumqi General Hospital of Lanzhou Military Region, Urumqi, Xinjiang, 830002, China; 2Department of
Nuclear Medicine, Urumqi General Hospital of Lanzhou Military Region, Urumqi, Xinjiang, 830002, China
Received March 3, 2012; accepted March 16, 2012; Epub March 25, 2012; Published March 30, 2012
Abstract: Background: Gastrointestinal stromal tumors (GISTs) are rare and our understanding of the natural history and optimal treatment of
GISTs are continually evolving. They are characterized by a remarkable cellular variability and their malignant potential is sometimes difficult to
predict. Case presentation: We report the case of intestinal stromal tumor in a 44 years old patient with a long history of anemia and recurrent
hemafecia. By using 99mTc-labeled red blood cell (99mTc-RBC) scintigraphy, extensive tracer accumulation in the jejunum was detected.
Immunohistochemically, the tumor strongly expresses the KIT (CD117) protein. The intestinal tumor was successfully resected with a
postoperative favorable outcome. Conclusion: 99mTc-RBC scintigraphy is an established technique for the identification and localization of
gastrointestinal bleeding. Abdominal scintigraphy appears to be a valuable supplement to conventional diagnostic methods for the diagnosis
of gastrointestinal stromal tumor hemorrhage. (IJCEP1203002).
Keywords: 99mTc-RBC, abdominal, scintigraphy, gastrointestinal stromal tumors
Address all correspondence to:
Dr. Rong Zhao
Department of Nuclear Medicine
Urumqi General Hospital of Lanzhou Military Region
Urumqi, Xinjiang, 830002, China.