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Int J Clin Exp Pathol 2012;5(5):463-467

Case Report
Solitary plasmacytoma of the bone involving young individuals, is there a role for
preceding trauma?

Whitney Pasch, Xiaohui Zhao, Sherif A Rezk

Department of Pathology & Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA

Received April 9, 2012; accepted May 13, 2012; Epub May 23, 2012; Published June 30, 2012

Abstract: Solitary plasmacytoma of the bone (SPB) is a rare plasma cell neoplasm that usually presents as a lytic lesion mainly localized
within the axial skeleton. The occurrence of SPB in young individuals is exceedingly rare but has been sporadically reported before. We report a
case of SPB involving a 21 year-old male with a prior history of trauma at the same site. We also reviewed all previous cases of SPB in young
individuals that were accessible to us to investigate the incidence of prior trauma in such cases and to investigate a potential role that trauma
may play in the pathogenesis of such lesions. (IJCEP1204002)

Keywords: Solitary plasmacytoma of the bone (SPB),  young individuals, trauma


Address all correspondence to:
Dr. Sherif A Rezk
Department of Pathology
University of California Irvine Medical center (UCI)
101 The City Drive, Bldg 54, Rm 4702
Orange, CA 92868, USA.
Tel: (714) 456-5009; Fax: (714) 456- 2394
E-mail: srezk@uci.edu