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Int J Clin Exp Pathol 2012;5(5):468-471

Case Report
Palatine tonsillar metastasis of lung cancer during chemotherapy

Wei Hong, Xian Wang, Xin-Min Yu, Bo Chen, Guo-Jun Ding, Yi-Ping Zhang

Department of Medical Oncology, Zhejiang Cancer Hospital, Zhejiang key laboratory of the diagnosis & treatment technology on thoracic
oncology, Hangzhou, China; Department of Medical Oncology, Biomedical Research Center, Sir Runrun Shaw Hospital, Medical School of
Zhejiang University, Hangzhou, China; Department of Pathology, and the Department of Radiology, Zhejiang Cancer Hospital, Zhejiang key
laboratory of the diagnosis & treatment technology on thoracic oncology, Hangzhou, China

Received April 17, 2012; accepted May 12, 2012; Epub May 23, 2012; Published June 15, 2012

Abstract: Malignant tumors in the tonsils are usually primary. Metastases to the tonsils are extremely rare, with nearly one hundred cases
reported. Herein we present an unusual case of palatine tonsillar metastasis of non-small cell lung cancer during chemotherapy. The patient
was a 39-year-old man who was diagnosed as non-small lung cancer with IIIA4 staging and poor differentiated histology. After two cycles of
vinorelbine and cisplatin based chemotherapy, a big mass was developed in the right palatine tonsil which was pathologically confirmed as
the metastasis from the lung. There was no hemorrhage and complains except moderate foreign body sensations. No cervical
lymphadenopathy and distal metastases to other organs such as brain and liver was found. Because of poor overall performance status, no
radiotherapy was given. The disease progressed after docetaxel treatment. To the best of our knowledge, this is the first case with palatine
tonsillar metastasis from non-small lung cancer during induction chemotherapy. (IJCEP1204005)

Keywords: Tonsil neoplasm, metastasis, lung neoplasm, computed tomography, histopathology


Address all correspondence to:
Dr. Yi-Ping Zhang
Department of Medical Oncology
Zhejiang Cancer Hospital
Zhejiang key laboratory of the diagnosis & treatment technology on thoracic oncology
Hangzhou, 310022, Zhejiang Province, China.
Tel: +86-751-88122182; Fax: +86-751-88122188
E-mail: zhangyp126@hotmail.com