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Int J Clin Exp Pathol 2012;5(7):710-714

Case Report
Cerebral metastasis of cervical cancer, report of two cases and review of the literature

Reza Setoodeh, Ardeshir Hakam, Yuan Shan

Department of Anatomic Pathology, Moffitt Cancer Center; Department of Pathology and Cell Biology, University of South Florida

Received June 6, 2012; Accepted July 27, 2012; Epub September 5, 2012; Published September 15, 2012

Abstract: Cervical cancers spread locally through the angiolymphatic apparatus and very rarely metastasize to the brain. The intracranial
metastasis is a late event and a sign of poor prognosis. We present two cases of uterine cervical carcinomas with brain metastasis presenting
with severe headaches in one case and hemiparesis and aphasia in the other one. Palliative craniotomy and debulking of the tumor was
performed in both patients. (IJCEP1205011).

Keywords: Cervical cancer, brain metastases, carcinoma of uterine cervix, intracranial metastasis, metastatic cervical cancer


Address all correspondence to:
Dr. Yuan Shan
H. Lee Moffitt Cancer Center and Research Institute
Department of Anatomic Pathology
University of South Florida
Tampa, FL, USA.
Tel: 813-745-3150
E-mail: yuan.shan@moffitt.org