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Int J Clin Exp Pathol 2012;5(9):977-981
Ectopic immature renal tissue: clues for diagnosis and management
Antonella Coli, Basilio Angrisani, Gaia Chiarello, Luca Massimi, Mariangela Novello, Libero Lauriola
Department of Anatomic Pathology and the Department of Pediatric Neurosurgery, Catholic University, Rome, Italy
Received August 6, 2012; Accepted September 19, 2012; Epub October 20, 2012; Published October 30, 2012
Abstract: Ectopic immature renal tissue has rarely been reported in literature, associated or not with teratoma. Its finding could be matter of
concern, owing to the occasional possibility that Wilms tumor may develop in this setting. We report a 1-year-old male patient who underwent
surgery for a sacral subcutaneous small teratoma with a prevalent component of immature renal tissue. The lesion appeared completely
excised and, in absence of features of malignancy, only follow-up was suggested. The patient was alive and well 15 months postoperatively.
Whenever ectopic immature renal tissue is detected, a proper histological interpretation is mandatory, in order to plan a suitable treatment of
the patient. From an extensive analysis of cases reported in literature we draw some practical suggestions for the diagnosis and treatment of
this rare condition. (IJCEP1208006).
Keywords: Ectopic renal tissue, wilms tumor, teratoma, metanephric tissue
Address all correspondence to:
Dr. Antonella Coli
Department of Anatomic Pathology
Catholic University, Largo F. Vito 1, 00168
Tel: +39-06-30154433; Fax: +39-06-3051343