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Int J Clin Exp Pathol 2012;5(9):1000-1006
Oncocytic lipoadenoma of the parotis gland: a report of a new case and review of the
Konstantinos T Mitsimponas, Abbas Agaimy, Tilo Schlittenbauer, Emeka Nkenke, Friedrich-Wilhelm Neukam
Department of Oral and Maxillofacial Surgery and Institute of Pathology, University Hospital, 91054 Erlangen, Germany. *Equal contributors.
Received August 17, 2012; Accepted September 15, 2012; Epub October 20, 2012; Published October 30, 2012
Abstract: Oncocytic lipoadenoma is a rare salivary gland tumour composed of adipose tissue and oncocytic epithelial cells in varied
proportions. This tumour is still not included in the current WHO classification of salivary gland neoplasms. We herein report a further case of
oncocytic lipoadenoma originating in the parotid gland of a 55-yearold woman. The tumour presented as a slowly growing asymptomatic
left-sided parotid gland mass. The resected tumour measured 2.7 cm in maximum diameter and was composed of oncocytoma-like epithelial
component admixed with mature adipocytes that made up 10% of the whole mass. Foci of sebaceous differentiation were seen. This rare
variant of lipomatous salivary gland tumours is in need of more recognition and should be distinguished from other fat-containing salivary
gland lesions, particularly lipomatous pleomorphic adenoma and myoepithelioma. (IJCEP1208016).
Keywords: Salivary gland tumours, oncocytes, sialolipoma, lipoadenoma
Address all correspondence to:
Dr. K T Mitsimponas
Mund-, Kiefer- und Gesichtschirurgische Klinik
Universitätsklinikum, Erlangen, Glückstraße 11,
91054 Erlangen, Germany.
Tel: 004991318543722; Fax: 004991318536288