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Int J Clin Exp Pathol 2013;6(3):516-520

Case Report
Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review

Yan Ning, Fanbin Kong, Janiel M Cragun, Wenxin Zheng

Obstetrics & Gynecology Hospital, Fudan University, Shanghai, China; Department of Pathology, University of Arizona College of Medicine,
Tucson, AZ, USA; Department of Obstetrics and Gynecology, University of Arizona, Tucson, AZ, USA; Arizona Cancer Center, University of
Arizo-na, Tucson, AZ, USA

Received December 18, 2012; Accepted January 18, 2013; Epub February 15, 2013; Published March 1, 2013

Abstract: Struma ovarii, as a monodermal variant of ovarian teratoma, constitutes about less than 3% of ovarian teratomas. It is difficult to be
macroscopically recognized. Multiple appearances under microscope serve as another reason to mislead the accurate pathologic evaluation.
Here, we report an unusual case of struma ovarii occurred in a 77 years old woman, which is currently known as the oldest age for this
disease. The frozen section morphologically showed sex cord like elements and was suspicious for a sex-cord stromal tumor, probably a
Sertoli cell tumor. Final pathological diagnosis was confirmed as struma ovarii based on the typical morphologic thyroid follicles and
immunohistochemical staining results. (IJCEP1212027).

Keywords: Struma ovarii, sertoli cell tumor, ovary

Address correspondence to: Dr. Yan Ning, Obstetrics & Gynecology Hospital, Fudan University, No. 419 Fang Xie Road, Shanghai, 200011,
China. Tel: +8602133189900; E-mail: nyiping@yahoo.com.cn