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Int J Clin Exp Pathol 2013;6(5):962-965

Case Report
Mucinous borderline tumor involving fallopian tube: case report and review of the
literature

Fangfang Liu, Junjian Wei, Danhua Shen, Jinsong Liu

Department of Pathology, Peking University People’s Hospital, Beijing 100044, China; Department of Pathology, The University of Texas MD
Anderson Cancer Center, Houston, TX 77030, USA; Department of Pathology, Evanston Hospital, Evanston, IL 60201

Received January 20, 2013; Accepted March 15, 2013; Epub April 15, 2013; Published May 1, 2013

Abstract: We report the case of a 74-year-old woman with a primary mucinous borderline tumor of the fallopian tube coexisting with an ovarian
mucinous borderline tumor. Data were obtained through histopathologic study of the excised surgical specimen. p53, estrogen receptor (ER)
and PAX8 expression were evaluated by immunohistochemistry on the available right fallopian tube and ovary. Both the ovarian and fallopian
tube borderline ovarian tumors were negative for p53, ER and PAX8. However, the staining pattern highlighted the transition from a normal
ciliated cell to neoplastic epithelia in the fallopian tube fimbria. This is the first report to indicate that mucinous borderline tumors may arise
from the ciliated cells at the fallopian tube fimbrial epithelia. ER and PAX8 are useful markers in identifying the transition and origination of
these tumors. (IJCEP1301045).

Keywords: Fallopian tube ciliated cells, primary mucinous borderline tumor, immunohistochemistry

Address correspondence to: Dr. Jinsong Liu, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
77030, USA. E-mail: jliu@mdanderson.org; Dr. Danhua Shen, Department of Pathology, Peking University People’s Hospital, Beijing 100044,
China. E-mail: shenpath59@yahoo.com.cn