IJCEP Copyright © 2007-All rights reserved.
Int J Clin Exp Pathol 2013;6(7):1448-1451

Case Report
Diagnosis and treatment of placental site trophoblastic tumor

Fengying Huang, Wenli Zheng, Qingchun Liang, Tuanfang Yin

Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China, 410011;
Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China, 410011; Department of
Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China, 410011; Department of Otolaryngology, The
Second Xiangya Hospital, Central South University, Changsha, Hunan, China, 410011

Received April 16, 2013; Accepted May 21, 2013; Epub June 15, 2013; Published July 1, 2013

Abstract: Here we report a case of a placental site trophoblastic tumor in a 36 year old Chinese woman, 31 months following a prior normal
pregnancy. Her clinical presentation and ultrasound findings were uncharacteristic; and the final definitive diagnosis was established based
on histological examination in conjunction with immunohistochemistry studies and a normal beta human chorionic gonadotropin level. The
tumor exhibited high grade histological features with tumor necrosis, nuclear atypia and high mitosis. The patient was successfully treated with
hysterectomy with pre- and post-operative chemotherapy. (IJCEP1304027).

Keywords: Placental site trophoblastic tumor (PSTT), gestational trophoblastic neoplasm (GTN), diagnosis, treatment

Address correspondence to: Dr. Tuanfang Yin, Department of Otolaryngology, The Second Xiangya Hospital, Central South University,
Changsha, Hunan, China, 410011. Phone: +8613874870794; E-mail: Ytfyin@163.com