IJCEP Copyright © 2007-All rights reserved.
Int J Clin Exp Pathol 2013;6(7):1437-1440

Case Report
Ectopic salivary gland tissue in a Rathke’s cleft cyst

Valentina Ranucci, Antonella Coli, Eleonora Marrucci, Mattogno Pier Paolo, Giuseppe Della Pepa, Carmelo Anile, Annunziato Mangiola

Department of Anatomic Pathology, Department of Neurosurgery, Catholic University, Rome, Italy

Received May 9, 2013; Accepted May 27, 2013; Epub June 15, 2013; Published July 1, 2013

Abstract: The presence of salivary gland tissue in the sella turcica has rarely been reported, mainly after pituitary examination at autopsy. Only
five symptomatic cases have previously been described, mainly associated with Rathke’s cleft cyst. We report a 17-year-old boy presenting with
headaches and hyperprolactinemia. The MRI showed a 19 mm sellar mass that at surgery revealed as a cystic lesion filled with mucinous
fluid. The histological examination documented the presence of ectopic salivary gland tissue in the wall of a Rathke’s cleft cyst. The present
report focuses on the possible pitfalls when dealing with unusual sellar lesions, and the need of increased awareness of this rare condition.

Keywords: Salivary gland tissue, pituitary, Rathke’s cleft cyst

Address correspondence to: Dr. Antonella Coli, Department of Anatomic Pathology, Catholic University, Largo F. Vito 1, 00168, Rome, Italy.
Tel: +39-06-30154433; Fax: +39-06-3051343; E-mail: antonella.coli@rm.unicatt.it