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Int J Clin Exp Pathol 2013;6(8):1693-1695

Case Report
Streptococcus agalactiae vaginitis: nonhemolytic variant on the Liofilchem® Chromatic
StreptoB

Vincenzo Savini, Roberta Marrollo, Marianna D’Antonio, Claudio D’Amario, Paolo Fazii, Domenico D’Antonio

Microbiology and Virology, Spirito Santo Hospital, Pescara (PE), Italy; Clinical Pathology, San Liberatore Hospital, Atri (TE), Italy

Received June 13, 2013; Accepted July 5, 2013; Epub July 15, 2013; Published August 1, 2013

Abstract: Streptococcus agalactiae (group B Streptococcus, GBS) vaginal pathogenicity is not uniformly acknowledged throughout the
literature; accordingly, in women, genital itching and burning, along with leukorrhea are commonly and almost exclusively referred to bacterial
vaginosis, candidiasis and trichomoniasis. Conversely, GBS virulence for vagina was recognized in the past, as the organism has been
observed to potentially cause local inflammation and discharge, as well as lactobacilli rarefaction. We depict here a case where a
nonhemolytic (γ-hemolytic) GBS strain was found to be the etiologic agent of vaginal infection. Such uncommon S. agalactiae phenotypes are
hard to be recognized and may be therefore responsible for misdiagnosing and underestimation of GBS vaginitis prevalence; here, we had the
support of the Liofilchem Chromatic ®StreptoB medium, that successfully detected such an atypical variant. (IJCEP1306010).

Keywords: Streptococcus agalactiae, group B antigen, GBS, vaginitis, leukorrhea

Address correspondence to: Vincenzo Savini, Microbiology and Virology, Spirito Santo Hospital, via Fonte Romana 8, CAP 65124, Pescara
(PE), Italy. Phone: 0039 340 7379737; E-mail: vincenzo_savini@libero.it