Case Report Mucinous Tubular and Spindle Cell Carcinoma of the Kidney with Sarcomatoid Differentiation
Rochelle A. Simon, MD, P. Anthony di Sant’Agnese, MD, Ganesh S. Palapattu, MD, Eric A. Singer, MD, Grace D. Candelario, MD, Jiaoti Huang, MD, PhD and Jorge L. Yao, MD
Departments of Pathology, Urology and Medicine University of Rochester Medical Center, Rochester, New York
Received 14 June 2007; accepted 24 June 2007; available online 1 January 2008
surgery were performed, but the patient died from disease progression three weeks postoperatively. MTSC is a recently recognized entity grade carcinoma, sarcomatoid differentiation may occur and lead to a fatal course, as in all other types of renal cell carcinomas. Adequate that is considered to be a low-grade carcinoma with a favorable prognosis. Our case demonstrates that although MTSC is usually a low-grade carcinoma, sarcomatoid differentiation may occur and lead to a fatal course, as in all other types of renal cell carcinomas. Adequate sampling and the exclusion of sarcomatoid differentiation in the spindle cell component are necessary for proper management and (IJCEP706001). prognostication. To our knowledge, this is the first reported case of MTSC with sarcomatoid differentiation and a fatal outcome. (IJCEP706001).
Address all correspondence to: Jorge L. Yao, MD, Genito-Urinary Pathology Section Department of Pathology and Laboratory Medicine University of Rochester Medical Center - Box 626 601 Elmwood Avenue, Rochester, NY, 14642 E-mail address: email@example.com. edu Phone: 585-273-1178 Fax: 585-273-3637